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voltage-clamp method

См. также в других словарях:

  • patch clamp — A specialized and powerful variant of voltage clamp method, in which a patch electrode of relatively large tip diameter (5 m m) is pressed tightly against the plasma membrane of a cell, forming an electrically tight, gigohm seal. The current… …   Dictionary of molecular biology

  • Patch clamp — The patch clamp technique is a laboratory technique in electrophysiology that allows the study of single or multiple ion channels in cells. The technique can be applied to a wide variety of cells but is especially useful in the study of excitable …   Wikipedia

  • Electrophysiology — (from Greek gr. ἥλεκτρον, ēlektron , amber [see the etymology of electron ] ; gr. φύσις, physis , nature, origin ; and gr. λογία, logia ) is the study of the electrical properties of biological cells and tissues. It involves measurements of… …   Wikipedia

  • Clamper (electronics) — Not to be confused with voltage clamp. Positive unbiased voltage clamping shifts the amplitude of the input waveform so that all parts of it are greater than 0 V A clamper is an electronic circuit that prevents a signal from exceeding a… …   Wikipedia

  • Ion channel — Not to be confused with: Ion Television or Ion implantation. Schematic diagram of an ion channel. 1 channel domains (typically four per channel), 2 outer vestibule, 3 selectivity filter, 4 diameter of selectivity filter, 5 phosphorylation site, 6 …   Wikipedia

  • Action potential — In physiology, an action potential is a short lasting event in which the electrical membrane potential of a cell rapidly rises and falls, following a consistent trajectory. Action potentials occur in several types of animal cells, called… …   Wikipedia

  • Hodgkin–Huxley model — Basic components of Hodgkin–Huxley type models. Hodgkin–Huxley type models represent the biophysical characteristic of cell membranes. The lipid bilayer is represented as a capacitance (Cm). Voltage gated and leak ion channels are represented by… …   Wikipedia

  • Quantitative models of the action potential — In neurophysiology, several mathematical models of the action potential have been developed, which fall into two basic types. The first type seeks to model the experimental data quantitatively, i.e., to reproduce the measurements of current and… …   Wikipedia

  • Krogh's Principle — states that For such a large number of problems there will be some animal of choice or a few such animals on which it can be most conveniently studied. This concept is central to those disciplines of biology that rely on the comparative method,… …   Wikipedia

  • Magnesium in biology — Magnesium is an essential element in biological systems. Magnesium occurs typically as the Mg2+ ion. It is an essential mineral nutrient for life[1][2][3] and is present in every cell type in every organism. For example, ATP (adenosine… …   Wikipedia

  • Morris–Lecar model — The Morris–Lecar model is a biological neuron model developed by Catherine Morris and Harold Lecar to reproduce the variety of oscillatory behavior in relation to Ca++ and K+ conductance in the giant barnacle muscle fiber.[1] Morris Lecar neurons …   Wikipedia

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